The inner life of your cells

I don't claim to understand most of this Harvard video regarding the inner life of cells, but I'm fascinated by the visuals. This 2006 video by Alain Viel, Robert A. Lue and John Liebler, functions as a biography about you (and me) and brings to mind the following passages from Harold M. Franklin's poetic/scientific book, The Way of the Cell, Page x (2001):

One response to the question, What Is Life?, is simply, Look around! Note the birds and butterflies, zebras and ammonites, the intricate web of life present and past, and joined the unending struggle to ensure its continuance in the face of human arrogance and mindlessness. This has been eloquently said by others, far better than I could, and it is not what I have in mind here. For the past 40 years, I’ve been immersed in research on the biochemistry and physiology of microorganisms, with emphasis on the fundamental aspects such as bioergetics and morphogenesis. In consequence, the central problems of life present themselves to me at the interface of chemistry and biology. How do lifeless chemicals come together to produce those exquisitely ordered structures that we call organisms? How can molecular interactions account for their behavior, growth, reproduction? How did organisms and their constituents arise on an Earth that had neither, and then diversify into the cornucopia of creatures that can live in each drop of pond water? My purpose is not to “reduce” biology to chemistry and physics, but to gain some insight into the nature of biological order. Inevitably, then, this is a personal book–one scientist’s attempt to wring understanding from the tide of knowledge. It grew out of the experience of a lifetime devoted to research, scholarship and instruction; but since my purpose is to make sense of the facts of life rather than to expound the facts themselves, this inquiry walks the edge of science proper. The arguments and conclusions presented here seem to me sound, but they are certainly not the last word on the subject. The most valuable lessons that the discipline of science teaches are to play the game of conjecture and reputation, to appreciate the provisional nature of our knowledge, and to prize doubt! If what I have written here encourages a few readers to look up from their gels and genes to peer at the far horizon, I shall be well content. Of my shortcomings as an investigator, scholar, philosopher and expository I am keenly aware . . .
Every month it seems that I hear yet another sad story about someone who has been stricken by a terrible disease or who has recently died. When they hear of these things, most people wonder, "How could this have happened?" Though I also mourn these events, I inevitably find myself wondering how bodies work at all. They seem far too complicated to work for even a second, much less for a lifetime. I know that they work, because I sitting here breathing and writing, but how is it possible that the extensive mechanical-seeming processes taking place within each of my cells successfully scale up to the organism level? Every breath is miraculous and every act of conscious generosity is beyond explanation (including religious "explanation"), at least to those of us who are honest.

Continue ReadingThe inner life of your cells

Father’s Day thoughts

I am the lucky father of two young ladies, aged 10 and 11. Though I have worked hard with my wife to raise these two girls for more than a few years, this work doesn’t qualify me as any sort of expert. I am a father like most other fathers, without any specialized training or insights regarding parenting. I think about my daughters every hour of every day, and that is no different than most other fathers. I am far too often away from home at work missing my daughters, often painfully so, but this is unfortunately typical in our culture. I want the best for my children, and in that regard, I am no different than any other father. I can’t imagine not having become a father, and that is another thought that occurs to virtually every other father. Though extolling fatherhood in writing is not something that all other fathers do, I am far from unique in this regard too. I work hard to respect the privacy of my daughters . It is not my right to freely disclose details about my relationship with either of my daughters to a large online audience. It is for this reason alone that you won’t read much about my relationships with my daughters (though here is a rare exception). I’m tempted to share thousands of joyous moments on this site, because these sorts of powerful moments happen every day. I don’t write about these private happenings, however, because it wouldn’t be fair. These privacy concerns won’t stop me from writing about fatherhood in general. Here I am, writing on “Father’s Day,” knowing full well that for all committed fathers, every day is Father’s Day. Every moment one sees one’s child beaming a smile, it is Father’s Moment. As I sit here tonight, I find myself thinking that this is an appropriate day for re-considering what it is that I’ve been trying to accomplish as a father. This sort of contemplation exercise was encouraged by the authors of a child-raising book called The Manipulative Child: How to Regain Control and Raise Resilient, Resourceful and Independent Kids, by E.W. Swihart and Patrick Cotter. These two authors encourage parents to periodically set aside the time to draft a concise statement of what it is that they are trying to accomplish as parents. We live in a scary world, and the ubiquitous dangers frame my views on parenting. I'm like most parents in that I constantly struggle to walk a fine line with my children. I want them to feel safe, but I also want to prepare them for the real world. It is in this context that I define my goal as a father something like this: When my daughters grow up to be adults, if they are still relying on me, or tending to my wants, putting me on any sort of pedestal or trying to please me, then I have failed as a father. When my daughters become adults, what I seek is a genuine friendship with each of them. In my view, a loving friendship is the sort of relationship that results between a parent and a child if the parenting has been successful. My hope is also that my daughters, once grown, will have developed the wide array of skills necessary to allow them to compete well with the global workforce, not merely the American workforce. I want them to also have the social skills (emotional intelligence) to allow them to confidently thrive both within and outside of groups. I want them to feel comfortable around many types of human beings, including those who have very few material resources. Nor do I want them to feel any obeisance when they find themselves in the company of people who have greater notoriety, power or material resources. I want them to be self-critical, such that they will want to repeatedly revisit their own most cherished presumptions (as well as those of others). And as my own mother told me, I want my daughters to be kind-hearted. Without going into any details, I am celebrating on this Father’s Day because I live with two kind-hearted, hard-working, self-critical, independent-minded daughters. There is a lot to celebrate today. My hope is that my beautiful daughters will continue their impressive journeys out into the world in order to make the world a better place, and to discover who they themselves are in the process. That is my Father’s Day hope.

Continue ReadingFather’s Day thoughts

I’ve located a hero

I'm creating a new post category called "heroes" in honor of high school student Keith Wagner, who obviously did some homework before handing this lying sack-of-shit politician his own head on a platter. This is unbelievable poise for a high school student. And then the politician, State Senator John Huppenthal of Arizona blessed the interview with a magnificent denouement: his unexplained absence. Or perhaps he had to leave because he was in the middle of a unanticipated panic-inspired bowel movement. I can only hope that mainstream journalists will note the successful formula used by Keith Wagner: Do your homework, go set up the interview, then don't let up. For full enjoyment, take a look at the comments regarding this video at Huffpo.

Continue ReadingI’ve located a hero

A new film about origami

I haven't yet seen this new film about origami, but based on this promo, I plan to. The film is called Between the Folds. It's the winner of the 2010 Peabody Award, as well as many other awards. What's this film about in more detail?

Between the Folds chronicles the stories of ten fine artists and intrepid theoretical scientists who have abandoned careers and scoffed at hard–earned graduate degrees—all to forge unconventional lives as modern–day paperfolders. As they converge on the unlikely medium of origami, these artists and scientists reinterpret the world in paper, and bring forth a bold mix of sensibilities towards art, expressiveness, creativity and meaning. And, together these offbeat and provocative minds demonstrate the innumerable ways that art and science come to bear as we struggle to understand and honor the world around us—as artists, scientists, creators, collaborators, preservers, and simply curious beings.

Continue ReadingA new film about origami