Statistical illiteracy afflicts health care professionals and their patients

Over at Scientific American Mind Gerd Gigerenzer and his colleagues have published a terrific article documenting the statistical illiteracy that sometimes runs rampant in health care fields. The article, "Knowing Your Chances," appears in the April/May/June 2009 edition. The authors point out numerous medical care fallacies caused by statistical illiteracy , including Rudy Giuliani's 2007claim that because 82% of Americans survived prostate cancer, compared to only 44% in England, that he was lucky to be living in the United States and not in England. This sort of claim is based on Giuliani's failure to understand statistics. Yes, in the United States, men will be more quickly diagnosed as having prostate cancer (because many more of them are given PSA tests), and then many more of them will be treated. Despite the stark differences in survival rates (the percentage of patients who survive the cancer for a least five years, "mortality rates in the two countries are close to the same: about 26 prostate cancer deaths per 100,000 American men versus 27 per 100,000 in Britain. That fact suggests the PSA test

has needlessly flagged prostate cancer in many American men, resulting in a lot of unnecessary surgery and radiation treatment, which often leads to impotence or incontinence. Because of overdiagnosis and lead-time bias, changes in five-year survival rates have no reliable relation to changes in mortality when patterns of diagnoses differ. And yet many official agencies continue to talk about five-year survival rates.

Gigerenzer and his colleagues give a highly disturbing as example regarding mammogram results. Assume that a woman just received a positive test result (suggesting breast cancer) and asks her doctor "What are the chances that I have breast cancer?" In a dramatic study researchers asked 160 gynecologists taking a continuing education course to give their best estimate based upon the following facts:

A.) the probability that a woman has breast cancer (prevalence) is 1% B.) if a woman has breast cancer the probability that she tests positive (sensitivity) is 90% C) if a woman does not have breast cancer, the probability that she nonetheless tests positive (false-positive rate) is 9% The best answer can be quickly derived from the above three statements. Only about one out of 10 women who test positive actually has breast cancer. The other 9/10 have been falsely diagnosed. Only 21% of physicians picked the right answer. 60% of the gynecologists believed that there was either an 81% or 90% chance that a woman with a positive test result actually had cancer, suggesting that they routinely cause horrific and needless fear in their patients. What I found amazing is that you can quickly and easily determine that 10% is a correct answer based upon the above three statements--simply assume that there are 100 patients, that one of them (1%) actually has breast cancer and that nine of them (9%) test false positive. This is grade school mathematics: only about 10% of the women testing positive actually have breast cancer. As the article describes, false diagnosis and bad interpretations often combine (e.g., in the case of HIV tests) to result in suicides, needless treatment and immense disruption in the lives of the patients. The authors also discuss the (tiny) increased risk of blood clots caused by taking third-generation oral contraceptives. Because the news media and consumers so often exhibit innumeracy, this news about the risk was communicated in a way that caused great anxiety. People learned that the third-generation pill increased the risk of blood clots by "100%." The media should have pack is aged the risk in a more meaningful way: whereas one out of 7000 women who took the second-generation pill had a blood clot, this increased to two in 7000 women who took the new bill. The "absolute risk increase" should have been more clearly communicated. Check out the full article for additional reasons to be concerned about statistical illiteracy.

Continue ReadingStatistical illiteracy afflicts health care professionals and their patients

Are you the same person you were several years ago?

Are you the same person you were several years ago? You think so, of course, because you are you. But think about the fact that virtually every atom in your body has changed over the years. Are you still you? A similar question was asked with regard to the Ship of Theseus, reported by Plutarch:

The ship wherein Theseus and the youth of Athens returned [from Crete] had thirty oars, and was preserved by the Athenians down even to the time of Demetrius Phalereus, for they took away the old planks as they decayed, putting in new and stronger timber in their place, insomuch that this ship became a standing example among the philosophers, for the logical question of things that grow; one side holding that the ship remained the same, and the other contending that it was not the same.

Many philosophers, ancient and contemporary, have weighed in on this fundamental question of ontology and flux, as reported by Wikipedia.

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Short dramatization of the Bible story of Lot and his daughters

I attended Catholic Church for many years as a child. I don't remember even once hearing any priest feature the story of Lot, the angels, and Lot's wife and daughters at Mass. Now I know why, of course. It's just so much easier to pretend that this story doesn't even exist in the Bible. It's much easier to cherry pick in order to maintain that every word in "the Bible" is the inspired literal teaching of God. Question: Do any of readers remember ever hearing any sort of priest, preacher or minister presenting the details of the story of Lot during any worship service? Here's the animated version of the story: Now maybe you're not into kinky sex. But maybe the Bible still has something for you. For instance, are you pro-slavery? So is God:

Continue ReadingShort dramatization of the Bible story of Lot and his daughters

My incredible neck surgery to fix my pinched nerves

I am so very lucky when it comes to health care options. It’s distressing to think of the millions of people live (and used to live) with deep or searing chronic pain who did not have this kind of treatment available. I was lucky to have good health insurance and highly competent doctors. No one, however, should have to deal with this sort of pain without treatment and hope. For the past two years, I’ve been struggling with a pinched nerve in my neck that caused serious pain in my left arm and left side of my back. On several occasions, I referenced some of the treatment I have been receiving, including this post on acupuncture, this post on the incredible fact that there is a skeleton inside my body, and this confession that I don’t do well when it comes to getting injections. I’ve had all kinds of conservative treatment, including intensive physical therapy. None of my conservative treatments worked. The most recent symptom was numbness several in my fingers (feeling in some of my fingers came back, but not in my left index finger). It's worth taking the time to tell you what my doctor told me about numbness. If you have it, permanent nerve damage is being done. If you don’t jump on it and address it quickly (within a matter of weeks), you might lose that sensation permanently. Numbness is different than pain, then, which doesn’t usually cause permanent injury. Because I had significant numbness, I had surgery, which occurred four days ago.

Continue ReadingMy incredible neck surgery to fix my pinched nerves

Jon Stewart skewers NBC’s White House documentary

Jon Stewart took on the role of a journalist covering "journalism" when he examined the exclusive White House story done by Brian Williams. Stewart is exactly right. Can you spell o-b-s-e-q-u-i-o-u-s? Yes, Williams' coverage of Obama's White House is shameful and vapid. Thank you, Jon Stewart, for exposing this "story" for what it was.

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Continue ReadingJon Stewart skewers NBC’s White House documentary