[P]eople who sat more than 11 hours a day had a 40% higher risk of dying in the next three years than people who sat less than four hours a day. This was
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after adjusting for factors such as age, weight, physical activity and general health status, all of which affect the death risk. It also found a clear dose-response effect: the more people sat, the higher their risk of death. The results are part of the Sax Institute’s 45 and Up Study, the largest ongoing study of healthy aging in the Southern Hemisphere. It compared the self-reported daily sitting time of 222,497 Australian adults 45 years or older with their likelihood of death in the next three years.
[M]en who sat more than six hours a day during the years of the study (1993 to 2006) were 18 percent more likely to die than those who sat for three hours or less. The death rate for women who sat more than six hours day was 37 percent over those who were seated three hours or less.